Methods and systems to minimize barcode exchange
US12163179B2 · kind B2 · utility
8Cited by
147References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 2, 2019 |
| Grant date | Dec 10, 2024 |
| Priority date | — |
| Expiry date | May 6, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/02027
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions to minimize barcode exchange during the preparation of barcoded next-generation sequencing libraries prepared from a single cell. The methods utilize oligonucleotides containing a 3′-terminated blocking group or sequences that prevent amplification or extension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.