Method of performing diffusion weighted magnetic resonance measurements

US12164013B2 · kind B2 · utility

Assignee

• The Brigham and Women's Hospital, Inc. · US

Inventors

• Irvin Teh · Leeds, GB
• Samo Lasic · Lund, SE
• Markus Nilsson · Espoo, FI
• Filip Szczepankiewicz · Lund, SE

Key dates

• Filing date: Jul 17, 2023
• Grant date: Dec 10, 2024
• Expiry date: Jul 17, 2043

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/10092
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A system and method for diffusion weighted magnetic resonance measurement includes performing a diffusion encoding sequence that comprises a diffusion encoding time-dependent magnetic field gradient g(t) with non-zero components gl(t) along two orthogonal directions (y, z), and a b-tensor having at least two non-zero eigenvalues. The gradient g(t) comprises a first and second encoding block. An n-th order gradient moment magnitude along direction l∈(y,z) is given by |Mnl(t)|=∫0tgl(t′)t′ndt′|, and the first encoding block is adapted to yield, at an end of the first encoding block, along y, |Mny(t)|≤Tn for each 0≤n≤m, where Tn is a predetermined n-th order threshold, and, along z, |Mnz(t)|≤Tn for each 0≤ n≤ m−1 and |Mnz(t)|>Tn for n=m. The second encoding block is adapted to yield, at an end of the second encoding block, along each one of l∈(y,z): |Mnl(t)|≤Tn for each 0≤n≤ m, wherein m is an integer order equal to or greater than 1.