Patent · US Active

Method for ameliorating, preventing or treating muscular atrophy or sarcopenia by administering composition comprising 2′-fucosyllactose as active ingredient

US12168020B2 · kind B2 · utility

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10Claims
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Assignee

Inventors

Key dates

Filing dateAug 26, 2022
Grant dateDec 17, 2024
Priority date
Expiry dateAug 26, 2042

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P21/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed is a method for preventing or treating muscular atrophy or sarcopenia, the method comprising administering a composition comprising 2′-fucosyllactose (2′-FL) as an active ingredient to a subject in need thereof. The composition administered to the subject increases the expression of genes related to mitochondrial function enhancement and mitochondrial biosynthesis, and reduces the expression of atrogin-1 and MuRF1 genes, which are markers for muscular atrophy, thereby providing effects of strengthening muscles and preventing muscular atrophy or sarcopenia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.