Methods of treating patients suffering from brain injury and methods of increasing the value of the extended Glasgow Outcome Scale of patients suffering from brain injury

US12171766B2 · kind B2 · utility

Assignee

• VERINOS OPERATIONS GMBH · DE

Inventors

• John Stover · Heidingsfeld, DE
• Frank Tegtmeier · Grevenbroich, DE

Key dates

• Filing date: Dec 2, 2022
• Grant date: Dec 24, 2024
• Expiry date: Dec 2, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to methods of treating a human patient suffering from brain injury. These method may comprise (starting) administering to a selected patient within a time period of ≤12 hours or within a time period of >12 hours after the occurrence of the brain injury a therapeutically effective amount of a biopterin compound such as 4-Amino-(6R,S)-5,6,7,8-tetrahydro-L-biopterin. The invention also relates to methods of increasing the value of the extended Glasgow Outcome Scale (eGOS) of patients suffering from brain injury, thereby improving the condition of the patient.