Patent · US Active

Non-protein Clostridial toxin compositions

US12171816B2 · kind B2 · utility

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259References
18Claims
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Assignee

Inventors

Key dates

Filing dateApr 18, 2023
Grant dateDec 24, 2024
Priority date
Expiry dateApr 18, 2043

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions that stabilize a Clostridial toxin active ingredient are described. The compositions can be liquid or solid compositions, and comprise a surfactant and an antioxidant. In some embodiments, the compositions comprise a surfactant selected from a poloxamer and a polysorbate; an antioxidant selected from methionine, N-acetyl cysteine, ethylenediaminetetraacetic acid and combinations thereof, and, optionally, a tonicity agent and/or a lyoprotector selected from, for example, trehalose, sucrose.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.