Patent · US Active

Anticancer and antifungal splice modulators

US12172988B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Michael D. Burkart · Boston, US
Warren C. Chan · Village of La Jolla, US
James J. La Clair · San Diego, US
Kelsey A. Trieger · Village of La Jolla, US
Catriona Jamieson · Village of La Jolla, US

Key dates

Filing date	Jan 12, 2022
Grant date	Dec 24, 2024
Priority date	—
Expiry date	Feb 2, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D407/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein, inter alia, are splice modulator compounds. The compounds include optically pure, stereospecific analogs of FD-895. The methods provided herein allow, for example, for scalable preparation of said compounds, and further allow, for example, use of said compounds for inhibiting spliceosome activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.