Patent · US Active

Peptide nucleic acid conjugates

US12173031B2 · kind B2 · utility

0Cited by
19References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 30, 2023
Grant dateDec 24, 2024
Priority date—
Expiry dateJan 30, 2043

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2458/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure is directed to conjugates of a specific binding entity and an oligomer, i.e. [Specific Binding Entity]-[Oligomer]n, wherein n is an integer ranging from 1 to 12, and where the Oligomer includes, in some embodiments, a PNA sequence having at least one substituent at a gamma carbon position. In some embodiments, the substituent at the gamma carbon position, e.g. an amino acid, a peptide, a miniPEG, or a polymer, includes at least one reporter moiety.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.