Polypeptide variants and uses thereof
US12173076B2 · kind B2 · utility
1Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 12, 2018 |
| Grant date | Dec 24, 2024 |
| Priority date | — |
| Expiry date | Jan 20, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/75
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
As described herein are polypeptides and antibodies having an Fc region and an antigen binding region where the Fc region has an Fc-Fc-enhancing mutation and a C1q binding-enhancing mutation providing for polypeptides or antibodies with increased CDC activity and/or agonistic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.