Fully stabilized asymmetric siRNA
US12173286B2 · kind B2 · utility
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39Claims
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Key dates
| Filing date | Jul 13, 2020 |
| Grant date | Dec 24, 2024 |
| Priority date | — |
| Expiry date | Mar 27, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are self-delivering oligonucleotides that are characterized by efficient RISC entry, minimum immune response and off-target effects, efficient cellular uptake without formulation, and efficient and specific tissue distribution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.