PaCas9 nuclease
US12173336B2 · kind B2 · utility
Inventors
- Dmitriy Aleksandrovich MADERA
- Aleksandr Vladimirovich KARABELSKII
- Roman Alekseevich IVANOV
- Dmitry Valentinovich MOROZOV
- Konstantin Severinov
- Sergey Shmakov
- Dmitrii Aleksandrovich Sutormin
- Georgii Evgenevich POBEGALOV
- Aleksandra Andreevna VASILEVA
- Polina Anatolevna SELKOVA
- Anatolii Nikolaevich ARSENIEV
- Tatyana Igorevna ZYUBKO
- Iana Vitalevna FEDOROVA
Key dates
| Filing date | Sep 13, 2019 |
| Grant date | Dec 24, 2024 |
| Priority date | — |
| Expiry date | Aug 11, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the field of biotechnology, molecular biology and medicine, in particular to nuclease enzyme and use thereof. More specifically, the present invention relates to PaCas9 nuclease enzyme. The invention also relates to a nucleic acid encoding the nuclease, a genetic construct, an expression vector, a delivery vector, which comprise the nucleic acid, a liposome comprising the nuclease or nucleic acid encoding the nuclease, a method for producing a nuclease, methods for delivery, and a host cell comprising a nucleic acid encoding the nuclease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.