Robotic sperm preparation in an intelligent automated in vitro fertilization and intracytoplasmic sperm injection platform
US12178475B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 2024 |
| Grant date | Dec 31, 2024 |
| Priority date | — |
| Expiry date | Feb 2, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V2201/03
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of artificial-intelligence-based robotic pipetting for spermatozoa preparation includes positioning a vessel containing a semen sample on a staging mechanism, wherein the staging mechanism includes at least one motor to position the vessel at a specified orientation, using an artificial intelligence/machine learning (AI/ML system) system. The method includes confirming a position of the vessel, using the AI/ML system. The method includes directing a robotic pipettor to place a pipette tip within the semen sample at a position specified by the AI/ML system. The method includes aspirating and mixing the semen sample using the robotic pipettor. The method includes receiving an image object from an imaging system that includes a microscopy system, a camera system, and a lighting system. The method includes determining a semen liquefaction state of the semen sample based at least in part on the image object, using the AI/ML system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.