Encapsulated gas or partial vacuum CT contrast material
US12178626B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 13, 2021 |
| Grant date | Dec 31, 2024 |
| Priority date | — |
| Expiry date | Sep 13, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an encapsulated gas or partial vacuum particle contrast media for use in CT imaging. In an exemplary embodiment, the invention provides an enteric contrast medium formulation. An exemplary formulation comprises, (a) an enteric contrast medium comprising a encapsulated gas or partial vacuum particle suspended in water. Exemplary encapsulated gas or partial vacuum particle has a specific gravity between 0.2 and 1.5. In various embodiments, the encapsulated gas or partial vacuum particle is suspended in aqueous media by an agent compatible with enteric administration of the formulation to a subject in need of such administration. In an exemplary embodiment, the contrast material is incorporated into a pharmaceutically acceptable carrier in which the material is suspended homogeneously. In an exemplary embodiment, the encapsulated gas or partial vacuum particle comprises 5% or more of the weight of the contrast material formulation. The invention also provides methods for imaging of the abdomen by dual energy CT or spectral CT contemporaneously with the delivery of the encapsulated gas or partial vacuum particle contrast material into the bowel lumen with…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.