Method for directing cellular migration patterns on a biological tissue
US12178700B2 · kind B2 · utility
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186References
19Claims
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Key dates
| Filing date | Mar 29, 2021 |
| Grant date | Dec 31, 2024 |
| Priority date | — |
| Expiry date | Jan 11, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB23K2103/32
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A contoured biological tissue for a bioprostheses, such as a cardiac/vascular patch or a bioprosthetic heart valve, and methods of contouring the tissue, are described. A predetermined pattern is provided on the tissue, comprising a plurality of ridges or depressions that are configured to facilitate cellular migration in a first direction and discourage cellular migration in a second direction. The biological tissue can be used in connection with a bioprosthetic heart valve comprising a biological tissue leaflet structure coupled to a supporting frame.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.