Device and method for compensating short-term pressure or volume fluctuations of a medium in a continuous biopharmaceutical process

US12179184B2 · kind B2 · utility

Assignee

• Sartorius Stedim Biotech GmbH · DE

Inventors

• Christian Grimm · Heilbad Heiligenstadt, DE
• Jochen Scholz · Lorch, DE
• Matthias Bode · Gemmenich, BE

Key dates

• Filing date: Dec 19, 2019
• Grant date: Dec 31, 2024
• Expiry date: Feb 10, 2042

Classification

• Technology area (CPC F): Mechanical Engineering; Lighting; Heating
• CPC primary: F16L55/04
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A device for compensating short-term pressure or volume fluctuations of a medium in a continuously managed biopharmaceutical process including a receiving space in fluid communication with a process line through which a medium flows, an equalizing space, which is separated from the receiving space by a deflectable element, and a counter-pressure mechanism in the equalizing space for applying a counter-pressure to the deflectable element towards the receiving space. A method of compensating short-term pressure or volume fluctuations of a medium in a continuously managed biopharmaceutical process including providing a receiving space in fluid communication with a process line through which a medium flows, receiving an excess amount of the medium flowing into the receiving space, charging an energy storage device by the medium flowing into the receiving space, and expelling at least part of the excess amount if the pressure or flow rate falls below a set amount.