Patent · US Active

Antigen binding molecule formats

US12180272B2 · kind B2 · utility

1Cited by

1References

11Claims

0Family size

Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Tong Zhang · Beijing, CN
Erica Pyles · New City, US
Michael Rosconi · New City, US
Nina Liu · Chappaqua, US
Supriya Patel · Mamaroneck, US
Eric Smith · New York, US
Andrew J. Murphy · Croton-on-Hudson, US
Chia-Yang Lin · Palo Alto, US
Samuel Davis · New York, US

Key dates

Filing date	Feb 7, 2022
Grant date	Dec 31, 2024
Priority date	—
Expiry date	Feb 7, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.