Patent · US Active

Antibodies binding human and monkey CD3 and uses thereof

US12180280B2 · kind B2 · utility

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17Claims
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Assignee

Inventors

Key dates

Filing dateAug 30, 2021
Grant dateDec 31, 2024
Priority date
Expiry dateAug 30, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/94
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed is a monoclonal antibody that binds human and monkey CD3, or an antigen-binding portion thereof, as well as the use of the antibody or antigen-binding portion thereof in treatment of inflammatory diseases and in preparation of bispecific antibodies. A bispecific antibody against e.g., CD3 and CD20 comprising the antibody or antigen-binding portion thereof of the disclosure, and the use of the bispecific antibody in treatment of diseases such as cancers are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.