Composition for detecting dsRNAs, comprising merocyanine compound and isomer thereof, and method for providing information for diagnosing cancer, by using dsRNA expression analysis
US12180537B2 · kind B2 · utility
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Key dates
| Filing date | Apr 19, 2019 |
| Grant date | Dec 31, 2024 |
| Priority date | — |
| Expiry date | Sep 11, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6883
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The merocyanine compound of the present invention causes a spectral change of a hypochromic shift in the vicinity of the wavelength of 512 nm by intercalation between dsRNA nucleotide pairs, and the spectral change shows high accuracy and reproducibility, so the merocyanine compound of the present invention can be effectively used for detecting dsRNA and comparing the expression levels between samples. In addition, the present invention relates to a composition for detecting dsRNA comprising a merocyanine compound, a salt thereof or an isomer thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.