Imaging system hardware

US12180543B2 · kind B2 · utility

Assignee

• 10x Genomics, Inc. · US

Inventors

• Cedric Uytingco · Milpitas, US
• Zachary Bent · Pleasanton, US
• Eswar Prasad Ramachandran Iyer · Pleasanton, US
• Fernandino Valdecanas · Tracy, US
• Meghan L. F. Frey · Livermore, US
• Steven W. Short · Pleasanton, US
• Yifeng Yin · Elk Grove, US
• Rajiv Bharadwaj · Pleasanton, US
• Joakim Lundeberg · Lidingö, SE
• Augusto Manuel Tentori · Dublin, US
• David Maurice Cox · Himmelried, CH
• Jennifer Chew · Union City, US
• Felice Alessio Bava · Roma, IT
• Linda Kvastad · Solna, SE
• Andrew David Price · San Diego, US

Key dates

• Filing date: Dec 6, 2019
• Grant date: Dec 31, 2024
• Expiry date: Dec 29, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2035/00752
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.