Patent · US Active

Factor VIII chimeric and hybrid polypeptides, and methods of use thereof

US12186375B2 · kind B2 · utility

0Cited by

38References

19Claims

0Family size

Assignee

BIOVERATIV THERAPEUTICS INC. · US

Inventors

Jennifer A. Dumont · Groton, US
Susan Low · Pepperell, US
Alan J. Bitonti · Acton, US
Glenn Pierce · Cambridge, US
Alvin Luk · Boston, US
Haiyan Jiang · Belmont, US
Byron McKinney · San Diego, US
Matt Ottmer · Newton, US
Jurg Sommer · Wayland, US
Karen Nugent · Owlswick, GB
Lian Li · Lexington, US
Robert T. Peters · Needham, US

Key dates

Filing date	Dec 4, 2020
Grant date	Jan 7, 2025
Priority date	—
Expiry date	Mar 7, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/31
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.