Patent · US Active

Polymer materials for delivery of short-chain fatty acids to the intestine for applications in human health and treatment of disease

US12186402B2 · kind B2 · utility

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23References
7Claims
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Key dates

Filing dateApr 19, 2023
Grant dateJan 7, 2025
Priority date
Expiry dateApr 19, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08F2438/03
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are polymer materials that find use in, for example, delivery of short-chain fatty acids. In particular, polymers are provided that form stable nanoscale structures and release their payload, for example, by cleavage of a covalent bond (e.g., via hydrolysis or enzymatic cleavage). The polymers are useful, for example, for delivery of payloads (e.g., SCFAs) to the intestine for applications in health and treatment of disease, and have broad applicability in diseases linked to changes in the human microbiota including inflammatory, autoimmune, allergic, metabolic, and central nervous system diseases, among others.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.