Patent · US Active

Blood treatment device comprising alkaline phosphatase

US12186472B2 · kind B2 · utility

0Cited by

1References

20Claims

0Family size

Assignee

GAMBRO LUNDIA AB · SE

Inventors

Jan Swartjes · Tübingen, DE
Markus Storr · Echterdingen, DE
Martin Rempfer · Gomaringen, DE
Isabelle LITZINGER · Hechingen, DE
Stefanie VOTTELER · Reutlingen, DE
Philipp Kuhn · Oberblockland, DE

Key dates

Filing date	Mar 6, 2020
Grant date	Jan 7, 2025
Priority date	—
Expiry date	Sep 21, 2041

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01D2323/2187
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

The invention relates to a blood treatment device configured to dephosphorylate extracellular adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and/or lipopolysaccharide (LPS) in the blood of a patient in need thereof in an extracorporeal blood circuit, wherein the device comprises a matrix having alkaline phosphatase (AP) immobilized thereon. The invention further relates to an extracorporeal blood circuit comprising a blood treatment device of the invention and to the blood treatment device for use as a medicament or to methods of treating an infection, preferably a blood or systemic infection, such as sepsis, and/or for the treatment of sepsis-associated acute kidney injury (AKI).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.