Methods and devices for mixing in a microfluidic system
US12186746B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 7, 2020 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | Jun 9, 2041 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/086
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for reducing sequencing by synthesis cycle time using a microfluidic device is provided. The microfluidic device comprises a flow cell having an inlet port, an outlet port, and a flow channel extending between the inlet port and the outlet port, wherein the flow channel receives an analyte of interest and one or more reagents for analyzing and detecting molecules. To aid in the acceleration of the reactions, the microfluidic device comprises a mixing device to increase the rates of diffusion of the reagents from the fluid bulk to an active surface of the flow cell. The mixing device comprises at least one of an electrothermal mixing device, an active mechanical mixing device, and a vibrational mixing device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.