Patent · US Active

Small molecule inhibitors of TEAD transcription factors

US12187722B2 · kind B2 · utility

0Cited by

7References

23Claims

0Family size

Assignee

The General Hospital Corporation · US

Inventors

Xu Wu · San Diego, US
Pranab Maiti · Narayanpur, IN
Chandrasekhar Abbineni · Hyderabad, IN
Krishna Chaitanya Talluri · Hyderabad, IN
Sunil Kumar Panigrahi · Dashapalla, IN
Gopala Krishna Jarugumilli · Malden, US
Yang Sun · Beijing, CN

Key dates

Filing date	Mar 13, 2020
Grant date	Jan 7, 2025
Priority date	—
Expiry date	Sep 28, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the TEAD transcription factor, and are useful in the treatment of diseases related to the activity of TEAD transcription factor including, e.g., cancer and other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.