Substituted benzimidazolone compounds

US12187723B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Alaric J. Dyckman · Lawrenceville, US
• Laxman Pasunoori · Warangal, IN
• Sreekantha Ratna Kumar · Bengaluru, IN
• Srinivasan Kunchithapatham Duraisamy · Hosur, IN
• Pitani Veera Venkata Srinivas · Polavaram, IN
• Vikram Bhogadi · Challodipalem, IN
• Subramanya Hegde · Kanchinakote, IN

Key dates

• Filing date: May 7, 2020
• Grant date: Jan 7, 2025
• Expiry date: Dec 16, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of Formula (I) N-oxides, or salts thereof, wherein G, A, R1, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.