Photon generating substrates for oligonucleotide synthesis
US12187760B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 26, 2021 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | Sep 27, 2041 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/1203
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Photon generating substrates for light-directed oligonucleotide synthesis are disclosed. Light is generated within a solid-state stack that supports growing oligonucleotides. The light may be generated by microLEDs, a pass-through liquid crystal panel, or an LCoS system. Light passes through a transmissive layer on which growing oligonucleotides are attached. Patterning of the light is controlled by selective activation of the microLEDs or by selective control of the transparency of a liquid crystal layer. Photolabile blocking groups are selectively removed by exposure to patterned light emitted from the photon generating substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.