Dithiolsaccharide mucolytic agents and uses thereof

US12187762B2 · kind B2 · utility

Assignees

• The Regents of the University of California · US
• University College Dublin · IE

Inventors

• Stefan Oscarson · Stockholm, SE
• John Vincent Fahy · San Francisco, US
• Irina Gitlin · San Francisco, US
• Wilfred Raymond · San Francisco, US

Key dates

• Filing date: Sep 10, 2019
• Grant date: Jan 7, 2025
• Expiry date: Dec 12, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a dithiolsaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.