Single-domain antibody binding to the G protein alpha
US12187793B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Jul 26, 2019 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | May 9, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a single-domain antibody (sdAb) which binds to the G protein alpha, comprising an amino acid sequence consisting of 3 CDR regions (CDR1 to CDR3) and 4 hinge regions (FR1 to FR4) according to the following formula (I): FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4 (I) and advantageously having a dissociation constant (Kd), measured in FRET, of less than 100 nM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.