Compositions and methods for making controls for sequence-based genetic testing
US12188012B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Apr 2, 2019 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | Jul 19, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/166
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are compositions that include nucleic acid fragments produced from double-stranded template nucleic acids, such as cell free DNA. The compositions can be used as positive or negative controls for quality of library preparation methods, calibration of an instrument such as a sequencing instrument, and/or a validation for a nucleic acid sequencing test. Also provided are methods for making the nucleic acid fragments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.