Patent · US Active

Expression cassette for production of high-expression and high-functionality target protein and use thereof

US12188036B2 · kind B2 · utility

0Cited by
2References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 11, 2018
Grant dateJan 7, 2025
Priority date
Expiry dateDec 19, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2840/44
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to an expression cassette for a target protein, comprising a promoter, a polynucleotide coding for the target protein, an intron sequence, and a poly A sequence, an expression vector, and a transformant. The expression cassette for a target protein according to the present invention can simultaneously perform the expression of the intron sequence and the target protein through one transduction and exhibits the effect of inducing the high expression and high functionality of the target protein by regulating the expression of an endogenous gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.