Method for enhancing gene expression using AAV vector
US12188040B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 26, 2019 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | Feb 7, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a composition for gene transfer comprising a recombinant virus vector and provides a composition for gene transfer which improves the efficiency of gene transfer using a virus vector. Specifically, the present invention provides a composition for gene transfer, which comprises a recombinant virus vector comprising a gene of interest for expression and a sugar at a concentration of at least 40 mM. The virus vector is preferably an adeno-associated virus vector. By using the composition of the present invention, the efficiency of gene transfer using a virus vector can be improved by about 50 times or more.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.