Guide RNA combinations and methods of use
US12188045B2 · kind B2 · utility
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4References
18Claims
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Key dates
| Filing date | Sep 8, 2022 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | Nov 22, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides gRNA compositions, CRISPR/Cas systems comprising the same, and methods of their use in the modification of immune effector cells. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.