Culture medium, coating matrix and method for expanding midbrain dopaminergic progenitor cells
US12188046B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Mar 9, 2023 |
| Grant date | Jan 7, 2025 |
| Priority date | — |
| Expiry date | Mar 9, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/50
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure described herein provides, inter alia, an expansion method for expanding mDAPs and a culture medium and a coating matrix combination used in the expansion method, as well as a maturation method for maturing mDAPs and a culture medium used in the maturation method. The present disclosure also provides a substantially homogeneous population of mDAPs and a substantially homogeneous population of mDANs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.