Nucleotide analogues and use thereof for nucleic acid sequencing and analysis preliminary class

US12188086B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Jingyue Ju · Englewood Cliffs, US
• Xiaoxu Li · New York, US
• Shiv Kumar · Montgomery, US
• Xin Chen · Lexington, US
• James J. Russo · New York, US
• Minchen Chien · Tenafly, US
• Steffen Jockusch · New York, US
• Chuanjuan Tao · Fort Lee, US
• Xuanting Wang · Braintree, US
• Sergey Kalachikov · New York, US
• Irina Morozova · The Bronx, US
• Shundi Shi · Queens, US

Key dates

• Filing date: Mar 14, 2019
• Grant date: Jan 7, 2025
• Expiry date: Nov 7, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2563/107
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention provides various orthogonal nucleotide analogues and methods for using combinations of said various orthogonal nucleotide analogues for sequencing by synthesis.