Patent · US Active

Use of bacterial extracellular vesicles as a biomarker for intestinal barrier permeability and microbial dysbiosis

US12188941B2 · kind B2 · utility

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0References

18Claims

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Assignee

UNIVERSITEIT GENT · BE

Inventors

An Hendrix · Heusden, BE
Olivier De Wever · Laarne, BE
Joeri Tulkens · Ledeberg, BE

Key dates

Filing date	Nov 21, 2019
Grant date	Jan 7, 2025
Priority date	—
Expiry date	May 7, 2042

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/06
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present disclosure relates to a method of analyzing a biofluid of a subject for the presence of bacterial extracellular vesicles (EV), the method comprising the steps of a) extracting bacterial EV from the biofluid, b) analyzing the bacterial EV-extracted molecular patterns for the presence of a disease marker, wherein the disease marker is a disease-specific molecular pattern of the subject; and the subject comprising patients diagnosed with HIV, IBD or cancer or the subject receiving a treatment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.