Nano-delivery carrier for targeted tumor administration and application thereof
US12194004B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 29, 2024 |
| Grant date | Jan 14, 2025 |
| Priority date | — |
| Expiry date | Jul 29, 2044 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nano-delivery carrier for targeted tumor administration and an application thereof are provided, which relate to the technical field of targeted anti-tumor dugs. A preparation method of the nano-delivery carrier for targeted tumor administration includes: mixing a NucA targeting a tumor and DSPE-PEG2000-NHS with DMF to obtain a mixture, adding triethylamine into the mixture, adjusting a pH of the mixture added with the triethylamine to 8-9 to react at room temperature, to thereby obtain the nano-delivery carrier for targeted tumor administration. An anti-tumor drug based on the nano-delivery carrier can correctly target to the tumor to be killed, for example, an anti-tumor drug based on the nano-delivery carrier and including RVT can target and kill ovarian cancer cells without damaging normal tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.