Patent · US Active

Glutarimide-containing pan-KRAS-mutant degrader compounds and uses thereof

US12195459B2 · kind B2 · utility

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46Claims
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Assignee

Inventors

Key dates

Filing dateApr 24, 2024
Grant dateJan 14, 2025
Priority date
Expiry dateApr 24, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.