Patent · US Active

Anti-PD-L1/anti-4-1BB bispecific antibodies and uses thereof

US12195538B2 · kind B2 · utility

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10Claims
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Key dates

Filing dateFeb 15, 2019
Grant dateJan 14, 2025
Priority date
Expiry dateMay 18, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure provides an anti-PD-L1/anti-4-1BB bispecific antibody capable to effectively block the interactions between PD-L1 and its receptor PD-1 and between 4-1BB and its ligand. The bispecific antibody may have high binding affinity to both of a PD-L1 protein and a 4-1BB protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.