High-throughput screening methods to identify small molecule targets
US12195730B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Aug 31, 2022 |
| Grant date | Jan 14, 2025 |
| Priority date | — |
| Expiry date | Aug 31, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/9108
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein are methods for identifying pairs of protein binding partners, mutations of which may inform the discovery of pharmaceutically useful small molecules. The methods disclosed herein may allow for the adaptation of the native protein degradation system to modulate specific disease targets at the protein level, in particular, for targets that have long been considered undruggable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.