Patent · US Active

RNA polymerase variants

US12195778B2 · kind B2 · utility

0Cited by

62References

12Claims

0Family size

Assignee

ModernaTX, Inc. · US

Inventors

Amy E. Rabideau · Waltham, US
Athanasios Dousis · Pasadena, US
Kanchana Ravichandran · Cambridge, US
Elissa Hobert · Cambridge, US

Key dates

Filing date	Aug 11, 2023
Grant date	Jan 14, 2025
Priority date	—
Expiry date	Aug 11, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/11023
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure provides, in some aspects, variant RNA polymerases, the use of which increases transcription efficiency while reducing the number of double-stranded RNA contaminates and run-on transcripts produced during an in vitro transcription reaction.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.