Dried amplification compositions

US12195792B2 · kind B2 · utility

Assignee

• GEN-PROBE INCORPORATED · US

Inventors

• Steven Mauch · San Diego, US
• Robert Stephen Dickson · San Diego, US
• Matthias Jost · Darmstadt, DE
• Mark E. FILIPOWSKY · San Marcos, US
• Donald Martin · Escondido, US
• Vladislav Nodelman · San Diego, US
• Cheryl Lynn Crowell · San Diego, US

Key dates

• Filing date: Feb 3, 2017
• Grant date: Jan 14, 2025
• Expiry date: Feb 3, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6804
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The disclosure provides dried compositions providing reagents for nucleic acid amplification, which are essentially free of inorganic salts. Lack of inorganic salts increases stability of such compositions and decreases formation of byproducts. Salts required for use of enzymes in the composition are supplied on reconstitution.