Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation
US12196661B2 · kind B2 · utility
1Cited by
114References
98Claims
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Key dates
| Filing date | Jun 6, 2024 |
| Grant date | Jan 14, 2025 |
| Priority date | — |
| Expiry date | Jun 6, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/1497
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A hydrogel particle, comprising a matrix comprising a polymerized monomer, said matrix comprising a plurality of micropores and a plurality of macropores, and one or more immunostimulatory biomolecules selected from the group consisting of an anti-CD3 antibody or antigen-binding fragment thereof, an anti-CD28 antibody or antigen-binding fragment thereof, and combinations thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.