Methods for simultaneous detection of analytes and apparatuses for practicing same
US12196750B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Feb 11, 2019 |
| Grant date | Jan 14, 2025 |
| Priority date | — |
| Expiry date | May 17, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2440/14
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are methods for simultaneously detecting analytes. The methods include exposing a tip of a nanosensor to a biological sample, measuring ionic current flow through the nanosensor tip to detect a first analyte and a second analyte in the biological sample, and distinguishing the first analyte from the second analyte based on a first diffusion limited current peak resulting from binding of a first specific binding member to the first analyte being distinguishable from a second diffusion limited current peak resulting from binding of a second specific binding member to the second analyte. Sensing apparatuses that find use, e.g., in practicing the methods of the present disclosure, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.