Immunoassay platform for the serological discrimination of closely related viruses
US12196755B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2021 |
| Grant date | Jan 14, 2025 |
| Priority date | — |
| Expiry date | Jul 30, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2470/12
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An immunoassay platform and methodology are described for discriminatively detecting target microorganism antibodies to a target antigen in a biological sample derived from a host animal, from among antibodies of cross-reactively-related microorganism(s) potentially present in the biological sample, by use of contemporaneous assays conducted with and without blocking antibodies exogenous to the host animal. Attenuation of detection reagent signal between the contemporaneous assays may be used to determine a target antigen previously infected or non-infected status of the host animal. An assay system is described, including: a single-use cartridge containing test strips constituted to perform the immunoassay; an integrated sample collection and processing device engageable with the single-use cartridge for delivery of sample thereto, and for operatively initiating immunoassay performance in the single-use cartridge; and a portable immunoassay reader for reading immunoassay output signals from the test strips of the single-use cartridge.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.