Patent · US Active

Adeno-associated virus compositions for restoring HBB gene function and methods of use thereof

US12201657B2 · kind B2 · utility

0Cited by

4References

3Claims

0Family size

Assignee

City of Hope · US

Inventors

Saswati Chatterjee · Altadena, US
Kamehameha Wong · Altadena, US
Marwa BenHajSalah · Duarte, US
Laura Jane Smith · Pasadena, US
Albert Barnes Seymour · Westborough, US
Jason Boke Wright · Concord, US
James McSwiggen · Boulder, US
Serena Nicole Dollive · Waltham, US
Thia Baboval St. Martin · Lunenburg, US
Jaime Michelle Prout · Hudson, US

Key dates

Filing date	Oct 17, 2018
Grant date	Jan 21, 2025
Priority date	—
Expiry date	Dec 3, 2041

Classification

Technology area (CPC A)Human Necessities
CPC primaryA01K2267/0381
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are adeno-associated virus (AAV) compositions for correcting a mutation in a beta globin gene (HBB) gene and methods of using the same to correct an HBB gene mutation in a cell. Also provided are packaging systems for making the adeno-associated virus compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.