Polygoni Milletii Rhizome compositions and methods of preparing the same

US12201665B2 · kind B2 · utility

Assignee

• SHAANXI PANLONG PHARMACEUTICAL CO., LTD. · CN

Inventors

• Xiaolin Xie · Xi'an, CN
• Dezhu Zhang · Xi'an, CN
• Chengyuan Liang · Xi'an, CN
• Shujun Ding · Xi'an, CN
• Yuzhi Liu · Xi'an, CN
• Zhao Ma · Xi'an, CN
• Xuhua Zhou · Xi'an, CN
• Zhong Meng · Seattle, US
• Jianguo Meng · Xi'an, CN

Key dates

• Filing date: Jul 1, 2022
• Grant date: Jan 21, 2025
• Expiry date: Jul 1, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2236/333
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of preparing a Polygoni Milletii Rhizome tincture includes: preparing a first mixture; extracting the first mixture with 70-90% ethanol under reflux condition to obtain a first extract solution; preparing a second mixture; extracting the second mixture with 50-70% ethanol to obtain a second extract solution; and mixing the first extract solution with the second extract solution to obtain the polygoni milletii rhizome tincture. A method of preparing a Polygoni Milletii Rhizome poultice includes: reparing a Polygoni Milletii Rhizome mixture; mixing the Polygoni Milletii Rhizome mixture and a skin penetration enhancer in water; mixing a moisturizing agent and a binder in water; adding a thickener in water; mixing methylparaben and ethylparaben in 90% ethanol; mixing all solutions to form a mixture; and applying the mixture on a non-woven fabric cloth and drying to form the Polygoni Milletii Rhizome poultice.