Method for increasing cell viability by using drug delivery system and ultrasound irradiation, and ultrasound irradiation apparatus using same
US12201798B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 31, 2019 |
| Grant date | Jan 21, 2025 |
| Priority date | — |
| Expiry date | Jan 16, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2007/0034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are a method for increasing the viability of cells by ultrasound irradiation and an ultrasound irradiation apparatus using same. The method comprises: applying a drug and an epidermal drug delivery system onto the epidermis of a subject; and, with ultrasound parameters each being preset within a certain range, an ultrasound irradiation apparatus irradiating ultrasound onto the epidermis of the subject through an ultrasound generation unit placed within a critical range from the epidermis of the subject, wherein the epidermal drug delivery system induces the formation of cavities, i.e., cavitation around the epidermis of the subject when the ultrasound is irradiated, the ultrasound parameters at least include an ultrasound pressure and an ultrasound duty percentage, the ultrasound pressure is 0.5-1 MPa, and the ultrasound duty percentage is 1-5%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.