Patent · US Active

Modified tetracycline for treatment of alcohol use disorder, pain and other disorders involving potential inflammatory processes

US12202785B2 · kind B2 · utility

0Cited by

0References

18Claims

0Family size

Assignee

TEXAS TECH UNIVERSITY SYSTEM · US

Inventors

Susan E. Bergeson · Lubbock, US
Peter Syapin · Camarillo, US
Ted W. Reid · Lubbock, US
Mayank Shastri · Vadodara, IN
Phat Tran · Lubbock, US

Key dates

Filing date	Nov 29, 2022
Grant date	Jan 21, 2025
Priority date	—
Expiry date	Dec 10, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/46
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method of treating Alcohol Use Disorder (AUD), Substance Use Disorder (SUD), tobacco use, pain, or proinflammatory disorders comprising: providing a subject with an effective amount of a modified tetracycline or derivative thereof to ameliorate or eliminate the AUD, SUD, tobacco use, pain, or proinflammatory disorder, and wherein the modified tetracycline or derivative thereof has reduced binding to a microbial ribosome and has the formula: wherein R1 is acetyl, R2 is OH or acetyl, R3 is acetyl, R4 is H or acetyl, and R5 is acetyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.