N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway
US12202826B2 · kind B2 · utility
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4References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 3, 2023 |
| Grant date | Jan 21, 2025 |
| Priority date | — |
| Expiry date | Apr 3, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to compounds. More specifically, the invention relates to compounds useful as inhibitors of the Wnt signalling pathway. Specifically, inhibitors of Porcupine (Porcn) are contemplated by the invention. In addition the invention contemplates processes to prepare the compounds and uses of the compounds. The compounds of the invention may therefore be used in treating conditions mediated by the Wnt signalling pathway, for example treating cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia; or enhancing the effectiveness of an anti-cancer treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.