Process for the production of DATH and intermediates thereof

US12202854B2 · kind B2 · utility

Assignee

• Galderma Holding SA · CH

Inventors

• Johan Olsson · Bromma, SE
• Kristoffer Bergman · Stockholm, SE

Key dates

• Filing date: May 16, 2022
• Grant date: Jan 21, 2025
• Expiry date: May 16, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H5/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present technology is directed to methods of producing 6,6′-diamino-6,6′-dideoxy-trehalose (“DATH”) or a salt thereof. The methods include optionally protecting one or more hydroxyl groups of D-trehalose and converting the primary hydroxyl groups of D-trehalose to produce DATH or a salt thereof through use of a halogen, azide, and/or protected amine. The present technology is also directed to intermediate products of the methods.