Methods and systems for preventing or reducing stenosis in a subject receiving a graft
US12208001B2 · kind B2 · utility
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4References
24Claims
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Assignee
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Key dates
| Filing date | Apr 28, 2022 |
| Grant date | Jan 28, 2025 |
| Priority date | — |
| Expiry date | Aug 2, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N5/0624
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system and a method of preventing or reducing stenosis in a subject is provided. The method includes implanting a passivated graft comprising vein into an artery. The implanting of the graft replaces and/or bypasses a diseased segment of the artery. The passivated graft including vein is prepared by exposing the exterior surface of the passivated graft comprising vein to a tissue structure stabilizing agent (“TSSA”) under conditions, including irradiation with light, sufficient to promote cross-linking of proteins within the vein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.